Environmental determinants of islet autoimmunity (ENDIA)

This study is for:

  • Pregnant women who have T1D

  • Fathers-to-be who have T1D

  • Expectant parents who have a child with T1D

  • Babies under 6 months of age who have a parent or sibling with T1D

About this study

The Environmental Determinants of Islet Autoimmunity (ENDIA) study aims to understand the environmental factors that act in the early stages of life to influence the risk for T1D. This knowledge will help with development of effective prevention strategies.

 

ENDIA will recruit 1400 pregnant women Australia-wide whose unborn child has a first degree relative (parent or sibling) with T1D. The study is recruiting families in South Australia, Western Australia, Victoria, New South Wales and Queensland. 

In Victoria, participants attend either the Royal Melbourne Hospital or the Geelong Hospital for three study visits during pregnancy, and then every three months after the baby is born for two years and every 6 months in the third year. There is also an option for families who live in regional areas to participate without traveling to Melbourne. Samples of blood, saliva and urine are collected from mother and baby during study visits and the mother fills out diet and lifestyle questionnaires.

ENDIA is the only study in the world investigating the connection between genes and environment in T1D from early pregnancy.

For more information about this study